(055) Effect of Loop Electrosurgical Excision Procedure (LEEP) on Female Sexual Function

Abstract Introduction Cancer of the uterine cervix is third most common gynecologic cancer and accounts for approximately 528,000 new cancers globally, on an annual basis. Cervical continues to be second leading cause death women aged 20 39. Human papillomavirus (HPV) infection responsible majority cervical cases. Screening with cell cytology in conjunction HPV testing effective screening technique that enables providers risk-stratify dysplasia subsequent development invasive cancer. Colposcopy a diagnostic utilized as follow-up abnormal test results. Depending adequacy colposcopy procedure patient’s histology, excisional may required. Loop electrosurgical excision (LEEP) one three techniques employed remove pre- cancerous transformation zone. Theoretically this “minimally invasive” approach reduces thermal injury surrounding structures, causes less intraoperative bleeding, creates smaller excised specimens. The aim minimize trauma compared other techniques. However, date, there have been no prospective studies examine effect biopsy patient-centered outcomes, such sexual satisfaction post-procedure dysfunction. A 2015 review article found only 6 examining There four published LEEP function, two them validated research questionnaires. Our university-based clinic performs 1000 colposcopies 100 procedures annually. Medical Faculty Associates practice care both racially socioeconomically diverse patient population. Objectives We plan conduct cohort study 736 comparing FSFI FSDS-R scores, prevalence dysfunction (defined < 26 points) among patients who undergo versus LEEP. Methods questionnaires will completed at their initial encounter after having pap smear. This questionnaire serve our baseline measurement. If did not need any additional procedures, they complete 12 weeks colposcopy. further required, procedure. Results are pending completion enrollment. Analyses controlled parity, age, menopausal status, psychotropic medication use, anxiety or depression diagnosis. Conclusions anticipate find difference score undergone interim results present upcoming conference. Disclosure No.